Prospective randomised treatment with recombinant human growth hormone in cystic fibrosis

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Prospective randomised treatment with recombinant human growth hormone in cystic fibrosis.

AIM To evaluate the efficacy and safety of treatment with recombinant growth hormone (rGH) in patients with cystic fibrosis (CF). METHODS Twenty patients with CF (aged 10-23 years) were randomised to age and sex matched treatment and control groups. The treatment group received daily subcutaneous injections of 1 IU/kg/wk rGH for 12 months. Pulmonary function (forced expiratory volume in one s...

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Recombinant human growth hormone in the treatment of patients with cystic fibrosis.

CONTEXT Recombinant human growth hormone (rhGH) improves growth in patients with growth hormone deficiency or idiopathic short stature. Its role in patients with cystic fibrosis (CF) is unclear. OBJECTIVE To review the effectiveness of rhGH in the treatment of patients with CF. METHODS Medline and the Cochrane Central Register of Controlled Trials were searched from the earliest date throug...

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Recombinant Human Growth Hormone in the Treatment of Patients With Cystic Fibrosis abstract

CONTEXT: Recombinant human growth hormone (rhGH) improves growth in patients with growth hormone deficiency or idiopathic short stature. Its role in patients with cystic fibrosis (CF) is unclear. OBJECTIVE: To review the effectiveness of rhGH in the treatment of patients with CF. METHODS: Medline and the Cochrane Central Register of Controlled Trials were searched from the earliest date through...

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The Role of Growth Hormone on Growth of Children with Cystic Fibrosis

Dear Editor,In spite of recent advances in treatment of infection and emphasis on adequate nutritional intake, patients with cystic fibrosis (CF) frequently have less than ideal body weight and adults are often shorter than their target height.1Owing to a state of relative growth hormone (GH) insensitivity, the anabolic and growth promoting effects of recombinant human GH (rhGH) treatment have ...

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the role of growth hormone on growth of children with cystic fibrosis

dear editor, in spite of recent advances in treatment of infection and emphasis on adequate nutritional intake, patients with cystic fibrosis (cf) frequently have less than ideal body weight and adults are often shorter than their target height. 1 owing to a state of relative growth hormone (gh) insensitivity, the anabolic and growth promoting effects of recombinant human gh (rhgh) treatment ha...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2003

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.88.12.1078